Anti-GPR52

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66594.100	100 µg		-	-	6 - 14 business days*		616.00€

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Protein function: Gs-coupled receptor activated by antipsychotics reserpine leading to an... more

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Product information "Anti-GPR52"

Protein function: Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241). May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241). Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228). [The UniProt Consortium]

Keywords:	Anti-G-protein coupled receptor 52
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66594

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthetic peptide corresponding to aa. 270-350 of Human GPR52
MW:	41 kD
Format:	Antigen Affinity Purified