Anti-GPR4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES11473.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES11473.100	100 µl		-	-	10 - 14 business days*		290.00€

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function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family., Protein... more

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Product information "Anti-GPR4"

function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family., Protein function: Proton-sensing G-protein coupled receptor couples to multiple intracellular signaling pathways, including GNAS/cAMP, GNAQ/phospholipase C (PLC), and GNA12/GNA13/Rho pathways (PubMed:12955148, PubMed:17462861, PubMed:22110680, PubMed:20211729). Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells through the GNA12/GNA13/Rho GTPase signaling pathway (PubMed:32058960). In the brain may mediate central respiratory sensitivity to CO(2)H(+). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cell membrane , Multi-pass membrane protein .

Keywords:	Anti-GPR4, Anti-GPR6C.l, Anti-G-protein coupled receptor 4, Anti-G-protein coupled receptor 6C.l, GPR4 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES11473

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthesized peptide derived from human protein . at AA range: 160-240
MW:	39 kD
Format:	Purified