Anti-GPR171

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES2457.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES2457.100	100 µl		-	-	10 - 14 business days*		290.00€

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function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family., Protein... more

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Product information "Anti-GPR171"

function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family., Protein function: G-protein coupled receptor for Big LEN, a 16-amino acid neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N). Acts through a G(i)-alpha-mediated pathway in response to Big LEN. Big LEN-GPR171 system plays an important role in regulating feeding and metabolism. Also plays a role in modulating fear and anxiety-like behaviors in the basolateral amygdala. Big LEN-GPR171 modulates the mu-type opioid receptor signaling and antinociception. Acts as a negative regulator T cell function (PubMed:34615877). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Cell membrane , Multi-pass membrane protein . Colocalized with GPR83 in the paraventricular nucleus. .

Keywords:	Anti-H963, Anti-G-protein coupled receptor 171, Anti-G-protein coupled receptor H963, GPR171 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES2457

Properties

Application:	WB, IF, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat, mouse,
Immunogen:	The antiserum was produced against synthesized peptide derived from human GPR171. AA range:181-230
MW:	36 kD
Format:	Antiserum