Anti-GPR17 (C-Term)

Anti-GPR17 (C-Term)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10136-1 1 each -

6 - 10 business days*

422.00€
 
GPR17 is a G protein-coupled receptor that has been identified as a dualistic receptor... more
Product information "Anti-GPR17 (C-Term)"
GPR17 is a G protein-coupled receptor that has been identified as a dualistic receptor recognizing signals from two unrelated chemical families: nucleotides and CysLTs. The deorphanization of GPR17 supports the suggested crosstalk between nucleotides and CysLTs during inflammation and injury. mRNA transcripts encoding this transmembrane receptor are most strongly expressed in the brain, kidney, and heart. Upon ischemic injury, GPR17 is upregulated in these tissues and its inhibition has been shown to decrease ischemic damage. This finding suggests GPR17 as a pharmacological target of ischemic injury. Cayman's peptide affinity-purified polyclonal antibody recognizes the C-terminal region of human GPR17. This protein exists in two isoforms, differing by 28 amino acids at the receptor N-terminus. The longer form of the protein consists of 367 amino acids with a calculated molecular weight of 41 kDa. The human and rat proteins share 89% amino acid identity. Post-translational modifications may explain the observed SDS-PAGE gel-migration to 57 kDa on immunoblot.Synonyms: G Protein-Coupled Receptor 17. Immunogen: Synthetic peptide from the C-terminal region of human GPR17. Formulation: (Request formulation change), 500 µl of peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: IHC and WB. UniProt Accession #: Q13304. Origin: Animal/Rabbit.
Keywords: Anti-R12, Anti-R12, Anti-GPR17, Anti-P2Y-like receptor, Anti-P2Y-like receptor, Anti-UDP/CysLT receptor, Anti-UDP/CysLT receptor, Anti-G-protein coupled receptor 17, Anti-G-protein coupled receptor 17, Anti-Uracil nucleotide/cysteinyl leukotriene receptor
Supplier: Cayman Chemical
Supplier-Nr: 10136

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, murine, rat
Immunogen: Synthetic peptide from the C-terminal region of human GPR17
Format: Solid

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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