Anti-GNL3L

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA036314.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA036314.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML.... more

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Product information "Anti-GNL3L"

Protein function: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 94%

Keywords:	Anti-GNL3L, Anti-Guanine nucleotide-binding protein-like 3-like protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA036314

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: HFLTAVAHRL GKKKKGGLYS QEQAAKAVLA DWVSGKISFY IPPPATHTLP THLSAEIVKE MTEVFDIED (ATA-APrEST78298)