Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPD, GAPDH)

Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPD, GAPDH)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G8140-03.100 100 µg - -

3 - 19 business days*

644.00€
 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative... more
Product information "Anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPD, GAPDH)"
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate , metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug'ml, Immunohistochemistry: 10ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: HeLa cell lysate, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: EC=1.2.1.12, EC=2.6.99.-, Anti-CDABP0047, Anti-Peptidyl-cysteine S-nitrosylase GAPDH, Anti-Glyceraldehyde-3-phosphate dehydrogenase
Supplier: United States Biological
Supplier-Nr: G8140-03

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide, 16 aapeptide from near the amino-terminus of human GAPDH (Genbank accession No. P04406).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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