Anti-GID8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES19882.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES19882.100	100 µl		-	-	10 - 14 business days*		290.00€

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Protein function: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively... more

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Product information "Anti-GID8"

Protein function: Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972). Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation (PubMed:28829046). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm . Nucleus . Localizes in the cytoplasm in the absence of Wnt stimulation and in the nucleus in the presence of Wnt stimulation. .

Keywords:	Anti-GID8, Anti-Twa1, Anti-Two hybrid-associated protein 1 with RanBPM, Anti-Glucose-induced degradation protein 8 homolog, GID8 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES19882

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human GID8 AA range: 115-165
Format:	Purified