Anti-GFPT1 (Glucosamine-fructose-6-phosphate Aminotransferase [Isomerizing] 1, GFPT, Glutamine:fruct

Anti-GFPT1 (Glucosamine-fructose-6-phosphate Aminotransferase [Isomerizing] 1, GFPT, Glutamine:fruct
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G2032-90H.100 100 µl - -

3 - 19 business days*

682.00€
 
GFAT1, glutamine:fructose-6-phosphate aminotransferase 1, is the rate-limiting enzyme of the... more
Product information "Anti-GFPT1 (Glucosamine-fructose-6-phosphate Aminotransferase [Isomerizing] 1, GFPT, Glutamine:fruct"
GFAT1, glutamine:fructose-6-phosphate aminotransferase 1, is the rate-limiting enzyme of the hexosamine biosynthesis pathway (1). This enzyme catalyzes the conversion of fructose-6-phosphate and glutamine to glucosamine-6-phosphate and glutamate (2). The hexosamine biosynthesis pathway generates the building blocks for protein and lipid glycosylation (2). Furthermore, studies suggest that increased activity of this pathway is a contributing factor to hyperglycemia-induced insulin resistance (1,2). GFAT1 is more active in non-insulin-dependent diabetes mellitus (NIDDM) patients (3). Transgenice mice overexpressing this enzyme in skeletal muscle and adipose tissue show an insulin resistance phenotype (4,5). Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight., Immunoprecipitation: 1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: EC=2.6.1.16, Anti-Hexosephosphate aminotransferase 1, Anti-D-fructose-6-phosphate amidotransferase 1, Anti-Glutamine:fructose 6 phosphate amidotransferase 1, Anti-Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1
Supplier: United States Biological
Supplier-Nr: G2032-90H

Properties

Application: IP, WB
Antibody Type: Monoclonal
Clone: 11C1035(D12F4)
Conjugate: No
Host: Rabbit
Species reactivity: human, rat
Immunogen: Synthetic peptide corresponding to the sequence around Gly100 of human GFAT1.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-GFPT1 (Glucosamine-fructose-6-phosphate Aminotransferase [Isomerizing] 1, GFPT, Glutamine:fruct"
Write a review
or to review a product.
Viewed