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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ6558 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Gephyrin is a protein that in humans is... more
Product information "Anti-Gephyrin / GPHN"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Gephyrin is a protein that in humans is encoded by the GPHN gene. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known. Protein function: Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Acts as a major instructive molecule at inhibitory synapses, where it also clusters GABA type A receptors (PubMed:25025157, PubMed:26613940). [The UniProt Consortium]
Keywords: | Anti-GPH, Anti-Domain E, Anti-Domain G, Anti-Gephyrin, Anti-MPT Mo-transferase, Anti-MPT adenylyltransferase, Anti-Molybdopterin adenylyltransferase, Anti-Molybdopterin molybdenumtransferase, Gephyrin Antibody / GPHN |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ6558 |
Properties
Application: | WB, IHC (paraffin), IF, Direct ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat, monkey |
Immunogen: | An E. coli-derived human protein (amino acids K148-L736) |
Format: | Purified |
Database Information
KEGG ID : | K15376 | Matching products |
UniProt ID : | Q9NQX3 | Matching products |
Gene ID | GeneID 10243 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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