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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| NSJ-V8963SAF-100UG | 100 µg | - | - |
7 - 12 business days* |
810.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. Geminin is a nuclear protein that regulates the... more
Product information "Anti-Geminin / GMNN, clone GMNN/3665"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Geminin is a nuclear protein that regulates the initiation of DNA replication during the cell cycle. Protein function: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) (PubMed:9635433, PubMed:14993212, PubMed:20129055, PubMed:24064211). It is degraded during the mitotic phase of the cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Its destruction at the metaphase- anaphase transition permits replication in the succeeding cell cycle (PubMed:9635433, PubMed:14993212, PubMed:24064211). Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing (PubMed:20129055). Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control (PubMed:22615398). [The UniProt Consortium]
| Keywords: | Anti-GMNN, Anti-Geminin, Geminin Antibody / GMNN |
| Supplier: | NSJ Bioreagents |
| Supplier-Nr: | V8963SAF |
Properties
| Application: | IF, IHC (paraffin) |
| Antibody Type: | Monoclonal |
| Clone: | GMNN/3665 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Immunogen: | A recombinant protein fragment |
| Format: | Apoptosis, Cell Cycle, DNA Repair |
Database Information
| KEGG ID : | K10749 | Matching products |
| UniProt ID : | O75496 | Matching products |
| Gene ID : | GeneID 51053 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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