Anti-GDF15 (GDF15, PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15, growth differentiation factor 15, P

Bone morphogenetic proteins (e.g., BMP9, MIM 605120) are members of the transforming growth factor-beta (see TGFB1, MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications have not been tested. , Recommended Dilutions: Peptide ELISA: 1:2000, Western Blot: 0.1-0.3ug/ml detects ~35kD band observed in human prostate lysates (calculated MW of 34.1kD according to NP_004855.1). In transfected HEK293 transiently expressing GDF15 a band of ~35kD is observed. This band is not observed in the non-transfected HEK293., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.