Anti-GDF15

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA011191.25	25 µl		-		7 - 10 business days*		264.00€
ATA-HPA011191.100	100 µl		-		7 - 10 business days*		393.00€

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Protein function: Regulates food intake, energy expenditure and body weight in response to... more

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Product information "Anti-GDF15"

Protein function: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL- expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 53% and to rat: 51%

Keywords:	Anti-NRG-1, Anti-MIC-1, Anti-NAG-1, Anti-GDF-15, Anti-Placental TGF-beta, Anti-NSAID-activated gene 1 protein, Anti-NSAID-regulated gene 1 protein, Anti-Prostate differentiation factor, Anti-Growth/differentiation factor 15
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA011191

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LSLAEASRAS FPGPSELHSE DSRFRELRKR YEDLLTRLRA NQSWEDSNTD LVPAPAVRIL TPEVRLGSGG HLHLRISRAA LPEGLPEASR LHRALFRLSP TASRSWDVTR PLRRQLSLAR PQAPALHLRL SPPPSQSDQL (ATA-APrEST72494)