Anti-GCM1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES16221.50	50 µl		-	-	10 - 15 business days*		173.00€
ELK-ES16221.100	100 µl		-	-	10 - 15 business days*		290.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded... more

Close menu

Product information "Anti-GCM1"

This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008], Protein function: Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes (PubMed:10542267, PubMed:18160678). Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer (PubMed:10542267). Binds to the SYDE1 promoter (PubMed:27917469). Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (PubMed:19219068). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000. Cellular localization: Nucleus .

Keywords:	Anti-GCM1, Anti-GCMA, Anti-hGCMa, Anti-GCM motif protein 1, Anti-Glial cells missing homolog 1, Anti-Chorion-specific transcription factor GCMa, GCM1 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES16221

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthesized peptide derived from human GCM1 AA range: 298-348
Format:	Purified