Anti-GATA4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA073899.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA073899.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and... more

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Product information "Anti-GATA4"

Protein function: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, sphingosine-1-phosphate lyase (PubMed:15734735). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 97%

Keywords:	Anti-GATA4, Anti-GATA-binding factor 4, Anti-Transcription factor GATA-4
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA073899

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PFDSPVLHSL PGRANPAARH PNLDMFDDFS EGRECV (ATA-APrEST93173)