Anti-GATA4

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG41629.100 100 µl - -

6 - 14 business days*

658.00€
 
Protein function: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and... more
Product information "Anti-GATA4"
Protein function: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac- specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735). [The UniProt Consortium]
Keywords: Anti-GATA4, Anti-GATA-binding factor 4, Anti-Transcription factor GATA-4
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG41629

Properties

Application: FC, ICC, IF, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of Human GATA4
MW: 44 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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