Anti-GAPDH

Anti-GAPDH
Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-901-BJ4 100 µg - -

6 - 10 business days*

684.00€
 
Anti-GAPDH Antibody is an IgY fraction antibody purified from monospecific chicken egg yolks by a... more
Product information "Anti-GAPDH"
Anti-GAPDH Antibody is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above. Cross reactivity with GAPDH from other sources has not been determined. Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D- glyceroyl phosphate. Component of the GAIT (gamma interferon- activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium]
Keywords: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=2.6.99.-, EC=1.2.1.12, Anti-Peptidyl-cysteine S-nitrosylase GAPDH, Anti-Glyceraldehyde-3-phosphate dehydrogenase
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-901-BJ4

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Chicken
Species reactivity: human, mouse, rat
Immunogen: 16 amino acid synthetic peptide from near the C-terminus of human GAPDH.

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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