Anti-GANP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-127A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-127A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Isoform GANP: Essential for the generation of high- affinity B-cells against... more

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Product information "Anti-GANP"

Protein function: Isoform GANP: Essential for the generation of high- affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation- dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells. Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. [The UniProt Consortium]

Keywords:	Anti-GANP, Anti-MCM3AP, EC=2.3.1.-, Anti-MCM3 acetyltransferase, Anti-MCM3 acetylating protein, Anti-80 kDa MCM3-associated protein, Anti-Germinal-center associated nuclear protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-127A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A303-127A-T maps to a region between residue 1 and 50 of human Germinal center-Associated Nuclear Protein using the numbering given in entry NP_003897.2 (GeneID 8888).
Format:	Antigen Affinity Purified