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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V7302-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V7302-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Galectin 1 is a... more
Product information "Anti-Galectin 1, clone GAL1/2499R"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival. Protein function: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. [The UniProt Consortium]
Keywords: | Anti-HBL, Anti-HPL, Anti-Gal-1, Anti-LGALS1, Anti-HLBP14, Anti-Galaptin, Anti-Galectin-1, Anti-14 kDa lectin, Anti-S-Lac lectin 1, Anti-Lactose-binding lectin 1, Anti-14 kDa laminin-binding protein, Anti-Lectin galactoside-binding soluble 1, Galectin 1 An |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V7302 |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | GAL1/2499R |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A human recombinant partial protein corresponding to amino acids 12-108 |
Format: | Purified |
Database Information
KEGG ID : | K06830 | Matching products |
UniProt ID : | P09382 | Matching products |
Gene ID | GeneID 3956 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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