Anti-Galectin 1, clone GAL1/1831

Anti-Galectin 1, clone GAL1/1831
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3201-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3201-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Galectin 1 is a... more
Product information "Anti-Galectin 1, clone GAL1/1831"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival. Protein function: Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. [The UniProt Consortium]
Keywords: Anti-HPL, Anti-HBL, Anti-Gal-1, Anti-LGALS1, Anti-HLBP14, Anti-Galaptin, Anti-Galectin-1, Anti-14 kDa lectin, Anti-S-Lac lectin 1, Anti-Lactose-binding lectin 1, Anti-14 kDa laminin-binding protein, Anti-Lectin galactoside-binding soluble 1, Galectin 1 An
Supplier: NSJ Bioreagents
Supplier-Nr: V3201-20UG

Properties

Application: ELISA, FC, IF, WB, IHC (paraffin)
Antibody Type: Monoclonal
Clone: GAL1/1831
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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