Anti-GAD65

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R30474	100 µg		-	-	3 - 10 business days*		772.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate decarboxylase or glutamic acid... more

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Product information "Anti-GAD65"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate decarboxylase or glutamic acid decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD65 is the isoform with molecular weight of 65 kDa. Karlsen et al.(1991) mapped the GAD2 gene to chromosome 10p13-p11.2 by in situ hybridization. Bu et al.(1992) isolated a cDNA corresponding to the GAD2 gene from a human brain cDNA library. The deduced 585-amino acid protein has a molecular mass of 65 kD. GAD65 is a target of auto-antibodies in people who later develop type 1 diabetes mellitus or latent auto-immune diabetes. Protein function: Catalyzes the production of GABA. [The UniProt Consortium]

Keywords:	Anti-GAD2, Anti-GAD65, Anti-GAD-65, EC=4.1.1.15, Anti-Glutamate decarboxylase 2, Anti-65 kDa glutamic acid decarboxylase, Anti-Glutamate decarboxylase 65 kDa isoform, GAD65 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R30474

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	An amino acid sequence from the N-terminus of the human protein (ENPGTARAWCQVAQKFT) was used as the immunogen for this GAD65 antibody (100% homologous in human, mouse and rat).
Format:	Purified