Anti-G3BP Recombinant

Anti-G3BP Recombinant
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-RC-7037.50 50 µl - -

Request delivery time estimate

232.00€
ABS-RC-7037.100 100 µl - -

Request delivery time estimate

332.00€
 
Protein function: ATP- and magnesium-dependent helicase that plays an essential role in innate... more
Product information "Anti-G3BP Recombinant"
Protein function: ATP- and magnesium-dependent helicase that plays an essential role in innate immunity (PubMed:30510222). Participates in the DNA- triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA (PubMed:30804210). In addition, plays an essential role in stress granule formation (PubMed:12642610, PubMed:20180778, PubMed:23279204). Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends (PubMed:9889278). Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency (PubMed:9889278). Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA (PubMed:9889278). Phosphorylation-dependent sequence-specific endoribonuclease in vitro (PubMed:11604510). Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR (PubMed:11604510). [The UniProt Consortium]
Keywords: Anti-Ras GTPase-activating protein-binding protein 1, Anti-G3BP-1, Anti-ATP-dependent DNA helicase VIII, Anti-hDH VIII, Anti-GAP SH3 domain-binding protein 1, Recombinant G3BP1 Antibody
Supplier: Absea
Supplier-Nr: RC-7037

Properties

Application: WB
Antibody Type: Monoclonal
Clone: 3L94
Conjugate: No
Host: Rabbit
Species reactivity: human, rat
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-G3BP Recombinant"
Write a review
or to review a product.
Viewed