Anti-FTL1 / Ferritin light chain, clone FTL/1387

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7412SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. Mammalian ferritins consist of 24 subunits made... more
Product information "Anti-FTL1 / Ferritin light chain, clone FTL/1387"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. Protein function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. [The UniProt Consortium]
Keywords: Anti-FTL, Anti-Ferritin L subunit, Anti-Ferritin light chain, FTL1 Antibody / Ferritin light chain
Supplier: NSJ Bioreagents
Supplier-Nr: V7412SAF

Properties

Application: WB, IHC (paraffin)
Antibody Type: Monoclonal
Clone: FTL/1387
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Amino acids 38-165 from the human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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