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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3322SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in 1X PBS, BSA free, sodium azide free. Follicle-stimulating hormone receptor (FSHR) is a... more
Product information "Anti-FSH Receptor, clone FSHR/1400"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Protein function: Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Induces cAMP production through the activation of PI3K-AKT and SRC-ERK1/2 signaling pathways. [The UniProt Consortium]
Keywords: | Anti-LGR1, Anti-FSHR, Anti-FSH-R, Anti-Follitropin receptor, Anti-Follicle-stimulating hormone receptor, FSH Receptor Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3322SAF |
Properties
Application: | FC, IHC, IF |
Antibody Type: | Monoclonal |
Clone: | FSHR/1400 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A human recombinant protein was used as the immunogen for this FSHR antibody. |
Format: | Purified |
Database Information
KEGG ID : | K04247 | Matching products |
UniProt ID : | P23945 | Matching products |
Gene ID | GeneID 2492 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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