Anti-FSH Receptor, clone FSHR/1400

Anti-FSH Receptor, clone FSHR/1400
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3322SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. Follicle-stimulating hormone receptor (FSHR) is a... more
Product information "Anti-FSH Receptor, clone FSHR/1400"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Protein function: Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Induces cAMP production through the activation of PI3K-AKT and SRC-ERK1/2 signaling pathways. [The UniProt Consortium]
Keywords: Anti-LGR1, Anti-FSHR, Anti-FSH-R, Anti-Follitropin receptor, Anti-Follicle-stimulating hormone receptor, FSH Receptor Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3322SAF-100UG

Properties

Application: FC, IHC, IF
Antibody Type: Monoclonal
Clone: FSHR/1400
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A human recombinant protein was used as the immunogen for this FSHR antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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