Anti-FRMD8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA005506.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA005506.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and... more

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Product information "Anti-FRMD8"

Protein function: Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cell surface (PubMed:29897333, PubMed:29897336). Negatively regulates Wnt signaling, possibly by antagonizing the recruitment of AXIN1 to LRP6 (PubMed:19572019). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 85% and to rat: 88%

Keywords:	Anti-iTAP, Anti-Bili, Anti-FRMD8, Anti-FKSG44, Anti-iRhom tail-associated protein, Anti-Band4.1 inhibitor LRP interactor, Anti-FERM domain-containing protein 8
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA005506

Properties

Application:	ICC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SREKHVLLGL RFQELSWDHT SPEEEEPILW LEFDGDSEGT PVNKLLKIYS KQAELMSSLI EYCIELSQAA EPAGPQDSAT GSPSDPSSSL APVQRPKLRR QGSVVSSRIQ HLSTIDYVED (ATA-APrEST86402)