Anti-Frizzled 2

Anti-Frizzled 2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG56583.100 100 µl - -

6 - 14 business days*

640.00€
 
Protein function: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the... more
Product information "Anti-Frizzled 2"
Protein function: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. [The UniProt Consortium]
Keywords: Anti-Fz-2, Anti-FZD2, Anti-hFz2, Anti-FzE2, Anti-Frizzled-2
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG56583

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide around aa. 208-260 of Human Frizzled 2
MW: 63.5 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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