Anti-FOXO3a

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-453A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A300-453A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Transcriptional activator which triggers apoptosis in the absence of survival... more

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Product information "Anti-FOXO3a"

Protein function: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. [The UniProt Consortium]

Keywords:	Anti-AF6q21 protein, Anti-Forkhead box protein O3, Anti-Forkhead in rhabdomyosarcoma-like 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-453A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: sheep, bovine, dog, horse, swine, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, african elephant, naked mole rat, thirteen-lined ground squirrel, domestic water buffalo)
Immunogen:	synthetic peptide. The epitope recognized by A300-453A-T maps to a region between residues 250 and 300 of human Forkhead Box O3a using the numbering given in Swiss-Prot entry O43524 (GeneID 2309).
Format:	Antigen Affinity Purified