Anti-FMR1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-BF6	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-FMR1 antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-FMR1"

Anti-FMR1 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. FMR1 antibody is human, mouse and rat reactive. Multiple isoforms of FMR1 are known to exist. Protein function: Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression. RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C). [The UniProt Consortium]

Keywords:	Anti-FMRP, Anti-FMR1, Anti-Protein FMR-1, Anti-Fragile X mental retardation protein 1
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-BF6

Properties

Application:	ELISA, IHC, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	19 amino acid peptide near the C-terminus of human FMR1.
Format:	Purified