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Protein function: Immunophilin protein with PPIase and co-chaperone activities. Component of... more
Product information "Anti-FKBP4/FKBP52"
Protein function: Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria. [The UniProt Consortium]
Keywords: | Anti-FKBP4, Anti-FKBP52, EC=5.2.1.8 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-426A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Reactivity: | Human, Mouse (Expected: Rat, Bovine, Rabbit) |
Immunogen: | synthetic peptide. The epitope recognized by A301-426A-T maps to a region between residue 1 and 50 of human FK506 binding protein 4 using the numbering given in entry NP_002005.1 (GeneID 2288). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K09571 | Find alternatives |
UniProt ID : | Q02790 | Find alternatives |
Gene ID | GeneID 2288 | Find alternatives |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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