Protein function: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex. [The UniProt Consortium]
Anti-FIP1, Anti-hFip1, Anti-FIP1L1, Anti-FIP1-like 1 protein, Anti-Factor interacting with PAP, Anti-Rearranged in hypereosinophilia, Anti-Pre-mRNA 3'-end-processing factor FIP1
synthetic peptide. The epitope recognized by A301-462A-T maps to a region between residue 544 and 594 of human factor interacting with PAP using the numbering given in entry NP_112179.2 (GeneID 81608).