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Product information "Anti-Ferritin (Capture/Detector)"
FTH (Ferritin Heavy Chain 1,also Proliferation-Inducing Protein 15,PIG15,and PlIF) is a 183 aa cytosolic and secreted protein.Human FTH is highly conserved among species and shares 93% and 95% aa identity with mouse and rat FTH,respectively. Stores iron in a soluble,non-toxic,readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Protein function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron (PubMed:24695223). [The UniProt Consortium]
Keywords:
Anti-FTL, Anti-Ferritin L subunit, Anti-Ferritin light chain, Ferritin Polyclonal Antibody(Capture/Detector)
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