Anti-FCGRT

Anti-FCGRT
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32149 100 µg - -

3 - 10 business days

503.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. IgG receptor FcRn large subunit p51 is a... more
Product information "Anti-FCGRT"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. In addition, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy. The FCGRT gene is closely situated to the DMPK gene, which is mutant in DM. Protein function: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. [The UniProt Consortium]
Keywords: Anti-FCRN, Anti-FcRn, Anti-FCGRT, Anti-Neonatal Fc receptor, Anti-IgG receptor FcRn large subunit p51, Anti-IgG Fc fragment receptor transporter alpha chain, FCGRT Antibody
Supplier-Nr: R32149

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: Amino acids 56-291 of human FCGRT were used as the immunogen for the FCGRT antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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