Anti-FBXO31

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-13238.20 20 µl -

7 - 16 business days*

71.00€
E-AB-13238.60 60 µl -

7 - 16 business days*

143.00€
E-AB-13238.120 120 µl -

7 - 16 business days*

238.00€
E-AB-13238.200 200 µl -

7 - 16 business days*

396.00€
 
This gene is a member of the F-box family. Members are classified into three classes according to... more
Product information "Anti-FBXO31"
This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. Protein function: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor. [The UniProt Consortium]
Keywords: Anti-FBX14, Anti-PP2386, Anti-FBXO31, Anti-F-box only protein 31, FBXO31 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-13238

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human FBXO31
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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