Anti-FBXO3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA002467.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3... more

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Product information "Anti-FBXO3"

Protein function: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%

Keywords:	Anti-FBX3, Anti-FBXO3, Anti-F-box only protein 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA002467

Properties

Application:	WB, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IGCKLPDDYR CSYRIHNGQK LVVPGLLGSM ALSNHYRSED LLDVDTAAGG FQQRQGLKYC LPLTFCIHTG LSQYIAVEAA EGRNKNEVFY QCPDQMARNP AAIDMFIIGA TFTDWFTSYV KNVVSGGFPI IRDQIFRYVH DPECV (ATA-APrEST89207)