Anti-FAM49B

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA009076.25 25 µl -

3 - 8 business days*

246.00€
ATA-HPA009076.100 100 µl -

3 - 8 business days*

491.00€
 
Protein function: Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling... more
Product information "Anti-FAM49B"
Protein function: Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling (PubMed:31285585, PubMed:30250061). Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE- induced actin polymerization (PubMed:30250061). Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE- mediated bacterial entry (PubMed:31285585). Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes. Involved in the regulation of mitochondrial dynamics and oxidative stress (PubMed:29059164). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-L1, Anti-BM-009, Anti-CYFIP-related Rac1 interactor B
Supplier: Atlas Antibodies
Supplier-Nr: HPA009076

Properties

Application: ICC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GNLLKVLTCT DLEQGPNFFL DFENAQPTES EKEIYNQVNV VLKDAEGILE DLQSYRGAGH EIREAIQHPA DEKLQEKAWG AVVPLVGKLK KFYEFSQRLE AALRGLLGAL TSTPYSPTQH LEREQALAKQ FAE (ATA-APrEST71588)

Database Information

UniProt ID : Q9NUQ9 | Matching products
Gene ID : GeneID 51571 | Matching products
Protein Atlas Nr. : ENSG00000153310

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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