Anti-FADD (human), mAb (1C4) (Biotin)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
AG-20B-0080B-C100	100 µg		-		3 - 9 business days*		308.00€

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Specificity: Recognizes the C-terminus of human FADD only in its unphosphorylated form. Protein... more

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Product information "Anti-FADD (human), mAb (1C4) (Biotin)"

Specificity: Recognizes the C-terminus of human FADD only in its unphosphorylated form. Protein function: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. [The UniProt Consortium]

Keywords:	Anti-GIG3, Anti-FADD, Anti-MORT1, Anti-Protein FADD, Anti-Growth-inhibiting gene 3 protein, Anti-FAS-associated death domain protein, Anti-Mediator of receptor induced toxicity, Anti-FAS-associating death domain-containing protein
Supplier:	AdipoGen Life Sciences
Supplier-Nr:	AG-20B-0080B

Properties

Application:	ELISA, WB, IP
Antibody Type:	Monoclonal
Clone:	1C4
Conjugate:	Biotin
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human FADD
Purity:	>95% (SDS PAGE)
Format:	Purified