Anti-EZH1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA077684.25	25 µl		-		7 - 10 business days*		239.00€
ATA-HPA077684.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex,... more

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Product information "Anti-EZH1"

Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 92%

Keywords:	Anti-EZH1, Anti-ENX-2, Anti-KIAA0388, Anti-Enhancer of zeste homolog 1, Anti-Histone-lysine N-methyltransferase EZH1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA077684

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: YKRKNKEIKI EPEPCGTDCF LLLEGAKEYA MLHNPRSKCS GRRRRRHHIV SASCSNASAS AVAETKEGDS DRDTGNDWAS SSSE (ATA-APrEST94472)