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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-RQ5576 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Exonuclease 1is an enzyme that in humans... more
Product information "Anti-Exonuclease 1 / EXO1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Exonuclease 1is an enzyme that in humans is encoded by the EXO1 gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. Protein function: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis. [The UniProt Consortium]
Keywords: | Anti-EXO1, Anti-EXOI, Anti-hExoI, Anti-hExo1, EC=3.1.-.-, Anti-Exonuclease I, Anti-Exonuclease 1, Exonuclease 1 Antibody / EXO1 |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | RQ5576 |
Properties
Application: | WB, FC, IHC (paraffin), Direct ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | human recombinant protein (amino acids M1-K294) |
Format: | Purified |
Database Information
KEGG ID : | K10746 | Matching products |
UniProt ID : | Q9UQ84 | Matching products |
Gene ID | GeneID 9156 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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