Anti-Exonuclease 1

Anti-Exonuclease 1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-640A-T 20 µl (2 blots) -

3 - 9 business days*

A302-640A-M 100 µl (10 blots) -

3 - 9 business days*

A302-640A 100 µl (20 µg) -

3 - 9 business days*

Protein function: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5'... more
Product information "Anti-Exonuclease 1"
Protein function: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch- containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis. [The UniProt Consortium]
Keywords: Anti-EXOI, Anti-EXO1, Anti-hExoI, Anti-hExo1, EC=3.1.-.-, Anti-Exonuclease 1, Anti-Exonuclease I
Supplier: Bethyl Laboratories
Supplier-Nr: A302-640A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Gorilla, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-640A-T maps to a region between residue 796 and 846 of human exonuclease 1 using the numbering given in entry NP_006018.3 (GeneID 9156).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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