Anti-ets-5

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Transcription factor that plays a role in the differentiation and function of the CO(2)- and O(2)-sensing BAG neurons (PubMed:21954162, PubMed:22479504, PubMed:30890567). The BAG neurons are required for the behavioral avoidance of environmental CO(2) and the sensing of decreased O(2) levels (PubMed:21954162, PubMed:22479504, PubMed:28193866). Promotes the expression of genes that play a role in CO(2)- and O(2)-sensing and in egg-laying in the BAG neurons (PubMed:21954162). Positively regulates the transcription of the receptor-type guanylate cyclase gcy-9, which is a critical component of the CO(2) transduction pathway, in the BAG neurons (PubMed:22479504). May mediate transcriptional activation by binding to the motif 5'- ACTTCCG-3' (PubMed:22479504, PubMed:30890567). Acts in the BAG and ASG neurons to regulate intestinal fat levels and to promote exploratory behavior, possibly by regulating neuropeptidergic signaling (PubMed:28193866). [The UniProt Consortium]