Anti-ETO

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-509A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A303-509A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

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Protein function: Transcriptional corepressor which facilitates transcriptional repression via... more

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Product information "Anti-ETO"

Protein function: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis. The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal (PubMed:23812588). [The UniProt Consortium]

Keywords:	Anti-AML1T1, Anti-RUNX1T1, Anti-Protein ETO, Anti-Protein MTG8, Anti-Protein CBFA2T1, Anti-Cyclin-D-related protein, Anti-Eight twenty one protein, Anti-Zinc finger MYND domain-containing protein 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-509A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide. The epitope recognized by A303-509A-T maps to a region between residue 554 and 604 of human Eight Twenty One Protein using the numbering given in entry NP_001185555.1 (GeneID 862).
Format:	Antigen Affinity Purified