Anti-ERLIN2 / SPFH2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41859.100	100 µl		-	-	10 - 15 business days*		616.00€

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Protein function: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic... more

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Product information "Anti-ERLIN2 / SPFH2"

Protein function: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618). [The UniProt Consortium]

Keywords:	Anti-C8orf2, Anti-ERLIN2, Anti-Erlin-2, Anti-SPFH domain-containing protein 2, Anti-Endoplasmic reticulum lipid raft-associated protein 2, Anti-Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41859

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	KLH-conjugated synthetic peptide between aa. 307-333 of Human ERLIN2 / SPFH2
MW:	38 kD
Format:	Purified