Anti-ERLIN2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA002025.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA002025.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic... more

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Product information "Anti-ERLIN2"

Protein function: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5- trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 95%

Keywords:	Anti-C8orf2, Anti-ERLIN2, Anti-Erlin-2, Anti-SPFH domain-containing protein 2, Anti-Endoplasmic reticulum lipid raft-associated protein 2, Anti-Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA002025

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KTKLLIAAQK QKVVEKEAET ERKKALIEAE KVAQVAEITY GQKVMEKETE KKISEIEDAA FLAREKAKAD AECYTAMKIA EANKLKLTPE YLQLMKYKAI ASNSKIYFGK DIPNMFMDSA GSVSKQFEGL ADKLSFGLED EPLETATK (ATA-APrEST78875)