Protein function: Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too. [The UniProt Consortium]
Anti-ERCC5, Anti-ERCM2, EC=3.1.-.-, Anti-DNA excision repair protein ERCC-5, Anti-DNA repair protein complementing XP-G cells, Anti-Xeroderma pigmentosum group G-complementing protein
synthetic peptide. The epitope recognized by A301-484A-T maps to a region between residue 650 and 700 of human excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) using the numbering given in entry NP_000114.2 (GeneID 2073).