Anti-ERCC1, clone 7F6-2A10-E8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG54172.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Isoform 1: Non-catalytic component of a structure- specific DNA repair... more

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Product information "Anti-ERCC1, clone 7F6-2A10-E8"

Protein function: Isoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. [The UniProt Consortium]

Keywords:	Anti-ERCC1, Anti-DNA excision repair protein ERCC-1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG54172

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	7F6-2A10-E8
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Purified recombinant human ERCC1 protein fragments expressed in E.coli
Format:	Affinity Purified