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Protein function: Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state (PubMed:16203728). Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728). [The UniProt Consortium]
Keywords:
Anti-Erbin, Anti-Protein LAP2, Anti-Densin-180-like protein, Anti-Erbb2-interacting protein
Human (Expected: Orangutan, Rhesus Monkey, Chimpanzee, Crab-eating Macaque)
Immunogen:
synthetic peptide. The epitope recognized by A303-763A-T maps to a region between residue 825 and 875 of human Erbb2 Interacting Protein using the numbering given in entry EAW51335.1 (GeneID 55914).
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