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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E3451-40M.100 | 100 µg | - | - |
3 - 19 business days* |
819.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
erbB4/HER4 is the fourth member of the human epidermal growth factor receptor (EGFR) family that... more
Product information "Anti-erbB4 (c-erbB4, HER4)"
erbB4/HER4 is the fourth member of the human epidermal growth factor receptor (EGFR) family that is frequently overexpressed in a variety of aggressive epithelial carcinomas. Its extracellular domain is most similar to the orphan receptor HER3, whereas its cytoplasmic kinase domain exhibits 79% and 77% identity with EGFR and HER2, respectively. HER4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain and cerebellum. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 detects erbB-4 on 10ug of A431 lysates., Immunohistochemistry: formalin-fixed, paraffin-embedded sections., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-4ICD, Anti-E4ICD, EC=2.7.10.1, Anti-s80HER4, Anti-p180erbB4, Anti-ERBB4 intracellular domain, Anti-Proto-oncogene-like protein c-ErbB-4, Anti-Receptor tyrosine-protein kinase erbB-4, Anti-Tyrosine kinase-type cell surface receptor HER4 |
Supplier: | United States Biological |
Supplier-Nr: | E3451-40M |
Properties
Application: | IHC, IP, WB |
Antibody Type: | Monoclonal |
Clone: | 9H232 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat |
Immunogen: | Synthetic peptide sequence RSTLQHPDYLQEYST from the cytoplasmic domain of the protein, residues 1250-1264. Cellular Localization: Isoform 1: Cell membrane, Single-pass type I membrane protein. & Isoform 2: Secreted. |
Format: | Purified |
Database Information
KEGG ID : | K05085 | Matching products |
UniProt ID : | Q15303 | Matching products |
Gene ID | GeneID 2066 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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