Anti-Eotaxin / CCL11

Anti-Eotaxin / CCL11
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32127 100 µg - -

3 - 10 business days

503.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CCL11 (Chemokine (C-C motif) ligand 11),... more
Product information "Anti-Eotaxin / CCL11"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CCL11 (Chemokine (C-C motif) ligand 11), also known as Eotaxin, is a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxin is a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12. Protein function: In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. [The UniProt Consortium]
Keywords: Anti-CCL11, Anti-SCYA11, Anti-Eotaxin, Anti-C-C motif chemokine 11, Anti-Small-inducible cytokine A11, Anti-Eosinophil chemotactic protein, Eotaxin Antibody / CCL11
Supplier-Nr: R32127

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: Amino acids 24-97 of human Eotaxin/CCL11 were used as the immunogen for the CCL11 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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