Anti-ENC-2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
200-901-BA4	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-ENC-2 Antibody is an IgY fraction antibody purified from monospecific chicken egg yolks by a... more

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Product information "Anti-ENC-2"

Anti-ENC-2 Antibody is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above. Cross reactivity with ENC-2 from other sources has not been determined. Protein function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E. [The UniProt Consortium]

Keywords:	Anti-ENC2, Anti-ENC-2, Anti-KLHL25, Anti-Kelch-like protein 25, Anti-Ectoderm-neural cortex protein 2
Supplier:	Rockland Immunochemicals
Supplier-Nr:	200-901-BA4

Properties

Application:	ELISA, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Chicken
Species reactivity:	human
Immunogen:	14 amino acid synthetic peptide near the internal region of human ENC-2.