Anti-ENAH / Mena, clone ENAH/1988

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7474SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. The Wiskott-Aldrich syndrome (WAS) is... more
Product information "Anti-ENAH / Mena, clone ENAH/1988"
1 mg/ml in 1X PBS, BSA free, sodium azide free. The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance. Protein function: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. ENAH induces the formation of F-actin rich outgrowths in fibroblasts. Acts synergistically with BAIAP2-alpha and downstream of NTN1 to promote filipodia formation. [The UniProt Consortium]
Keywords: Anti-ENAH, Anti-MENA, Anti-Protein enabled homolog, ENAH Antibody / Mena
Supplier: NSJ Bioreagents
Supplier-Nr: V7474SAF

Properties

Application: WB
Antibody Type: Monoclonal
Clone: ENAH/1988
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: A portion of amino acids 485-589 from the human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-ENAH / Mena, clone ENAH/1988"
Write a review
or to review a product.
Viewed