Anti-EMD

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA000609.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA000609.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Stabilizes and promotes the formation of a nuclear actin cortical network.... more

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Product information "Anti-EMD"

Protein function: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta- catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1- dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 71% and to rat: 73%

Keywords:	Anti-EMD, Anti-EDMD, Anti-Emerin
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA000609

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ASSYSFSDLN STRGDADMYD LPKKEDALLY QSKGYNDDYY EESYFTTRTY GEPESAGPSR AVRQSVTSFP DADAFHHQVH DDDLLSSSEE ECKDRERPMY GRDSACQSIT HY (ATA-APrEST74058)